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Happy Government Funding Expiration Week!
Here’s an actual photo of me taking a break from C-SPAN 🤣 👇️
Notioly Collection of Royalty-Free Photos
Just kidding.
Let’s see if we hit government shutdown or not.
Anyway,
I owe you Part Two of my last newsletter. I didn’t forget, but haven’t put it together yet. It’ll be good, I promise. 🤞
The JAMA Open Forum email came today and they shared their “Most Viewed Articles in 2024.” Here’s the full list 👇️
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Here’s a down and dirty summary of the findings of a few of the articles. These are far cries from substitutes for reading them yourself, but sometimes a quick takeaway is all you have time for!
I also just like seeing what other people like to read 🤓 👀📰
The investigators did not find support for an association between multivitamin use and mortality in this 20-year cohort study.
My takeaway: multivitamin value leads to more expensive urine but is likely not a valuable way to deploy personal healthcare spending resources.
GLP-1s may reduce the risk of diabetic patients getting 10 of the 13 specific obesity associated cancers (OACs) when compared to diabetic patients using insulin to manage their blood sugar. The 10 cancers: gallbladder, meningioma, pancreatic, hepatocellular, ovarian, colorectal, multiple myeloma, esophageal, endometrial, kidney.
My takeaway: The investigators suggest more pre-clinical and clinical research after the results of their work. We have a lot left to learn about the impacts of these medications and for whom they are most appropriately indicated. Would the reduction in obesity-related cancers be the same for those taking the GLP-1 for obesity without T2D?
This large, 28 year cohort study identified a 28% lower risk of dementia death compared to those who never or rarely consumed olive oil, regardless of the quality of diet overall. This study was done in the U.S. vs. other countries with a commonly higher olive oil consumption. The association between olive oil and reduced risk of dementia was stronger in women than men.
My takeaway: Dementia is on the rise, straining the healthcare system and care continuum as well as caregivers. Interest in dementia-related care has grown in the last few years, and new resources are being devoted to helping manage these conditions more effectively upstream. Olive oil is certainly an easy swap from other options. There may be value in using olive oil to reduce dementia risk.
(In my very first newsletter post, sent in October of last year, I wrote about the Blue Zones and the very low dementia risk there. Here’s a link to the second post, on GUIDE not long after it was announced.)
So—-
Don’t waste money on multivitamins,
Consider GLP-1s for T2D vs. metformin to potentially lower the risk of 10 of the 13 obesity-related cancers,
and
Olive oil may help protect against dementia. Especially in women.